The ABCs of CPP
The phase of life during which children transition into adults.
A male sex hormone (like testosterone, for example)
An X-ray of the left hand/wrist that helps determine how a patient’s skeleton is maturing compared to their chronological age.
When the breast develops into a small mound and areola diameter increases, signifying puberty.
A rare, treatable condition where the brain releases the puberty-inducing hormone (GnRH) too soon. This results in puberty before the age of 8 in girls and 9 in boys.
The sex hormone responsible for the development and regulation of feminine body characteristics and the female reproductive system.
A hormone secreted by the brain’s pituitary gland that controls menstrual cycles and egg formation in females and promotes the production of sperm in males. FSH release is triggered by GnRH.
The first instance of gonadal puberty symptoms, which entails the development of ovaries and increased estradiol production in females and the development of testes and testosterone in males.
A hormone that, when secreted from the brain’s pituitary gland, triggers the release of follicle-stimulating hormone and luteinizing hormone, causing puberty.
A type of GnRH agonist that treats CPP by blocking the release of gonadotropin-releasing hormone, pausing puberty.
Chemical substances in the body that serve as messenger molecules, telling other cells and organs how to function.
The region of the brain (beneath the thalamus) that coordinates the pituitary gland, controlling sexual development and basic body functions.
When the cause of a medical condition is unknown, as is often the case with CPP.
A type of GnRH agonist that treats CPP by blocking the release of gonadotropin-releasing hormone, pausing puberty.
A hormone secreted by the brain’s pituitary gland that stimulates ovulation in females and androgen development in males. Luteinizing hormone is triggered by GnRH.
A girl’s first occurrence of menstruation.
A doctor who specializes in the diagnosis and treatment of children with endocrine conditions such as diabetes, growth disorders, and precocious puberty.
One of two types of precocious puberty occurring due to the excess production of estrogen or testosterone.
A pea-sized gland in the base of the brain that helps control the growth and function of other endocrine glands.
The first appearance of pubic hair at the start of puberty.
A hormone that affects the growth and/or function of the reproductive organs, such as estrogen, progesterone, and testosterone.
The sex hormone responsible for the development and regulation of masculine body characteristics and the male reproductive system.
A type of GnRH agonist that treats CPP by blocking the release of gonadotropin-releasing hormone, pausing puberty.

